Closed Loop System on the Base of Non-Invasive Optical Glucometer

Closed loop system for diabetes mellitus compensation was developed. The system comprises a non-invasive optical glucose meter, an insulin infusion device and algorithm for blood glucose prediction. Glucometer consists of the control unit connected to the earlap clip by optical fiber. Experimental trials show that inherent accuracy of the optical system is 0.012 %, reproducibility – 0.06 %, RMSE in the blood glucose physiological area ¬– 17 %. The system was provided with the short-term prediction algorithm, which corrects 96.5 % cases of inaccurate operation of the glucometer that makes insulin infusion more physiological. The system is aimed for personal continuous blood glucose control for patients with diabetes mellitus type I.